Azilsartan Medoxomil+cilnidipine
About Azilsartan Medoxomil+cilnidipine
Azilsartan Medoxomil+cilnidipine belongs to the class of drugs called anti-hypertensive agents primarily used to treat high blood pressure (hypertension). Hypertension is a medical condition in which the blood pressure is elevated persistently in the arteries. High blood pressure is mostly caused by obesity, diabetes, smoking, high salt intake, stress, lack of physical activity or ageing.
Azilsartan Medoxomil+cilnidipine consists of two medicines, Azilsartan Medoxomil and Cilnidipine. Azilsartan Medoxomil is an angiotensin receptor blocker (ARB) that works by blocking the hormone angiotensin. This helps relax the blood vessels, allowing the blood to flow more smoothly and the heart to pump more efficiently. Cilnidipine is a calcium channel blocker that acts by relaxing the blood vessels. This reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body. Together, Azilsartan Medoxomil+cilnidipine helps lower raised blood pressure.
Your doctor will decide the dosage and duration based on your medical condition. In some cases, Azilsartan Medoxomil+cilnidipine can cause side effects like nausea, taste changes or altered taste, stomach upset or GI disturbances, diarrhoea, headache, weakness, peripheral oedema, tachycardia, palpitations, dizziness or tiredness, lethargy (a lack of energy), and decreased blood pressure (hypotension). Most of these side effects of Azilsartan Medoxomil+cilnidipine do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.
Before taking Azilsartan Medoxomil+cilnidipine, inform your doctor about all your medical conditions, sensitivities, and medications you are using. Even if you feel better, do not stop taking your medication. Azilsartan Medoxomil+cilnidipine should not be used in pregnant women and the paediatric population. Check with the doctor if you are breastfeeding. A decision should be made whether to discontinue nursing or to discontinue the medicine, taking into account the importance of the medicine to the mother. Azilsartan Medoxomil+cilnidipine may cause side effects like dizziness or tiredness. Hence, it is recommended not to drive or operate machinery until you are alert.
Uses of Azilsartan Medoxomil+cilnidipine
Medicinal Benefits
Azilsartan Medoxomil+cilnidipine consists of two medicines, Azilsartan Medoxomil and Cilnidipine. Azilsartan Medoxomil is an angiotensin receptor blocker (ARB) that blocks the hormone angiotensin. This helps relax the blood vessels, allowing the blood to flow more smoothly and the heart to pump more efficiently. Cilnidipine is a calcium channel blocker that acts by relaxing the blood vessels. This reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body. Together, Azilsartan Medoxomil+cilnidipine helps lower raised blood pressure.
Directions for Use
Storage
Side Effects of Azilsartan Medoxomil+cilnidipine
- Nausea
- Taste changes or altered taste
- Stomach upset
- Diarrhoea
- Headache
- Weakness
- peripheral oedema
- Tachycardia
- Palpitations
- GI disturbances
- Dizziness or tiredness
- Lethargy (a lack of energy)
- Decreased blood pressure (hypotension)
Drug Warnings
It is recommended not to use if you are allergic or hypersensitive to any component present in Azilsartan Medoxomil+cilnidipine. Do not stop taking Azilsartan Medoxomil+cilnidipine without your doctor's advice. Sudden stopping of Azilsartan Medoxomil+cilnidipine may cause changes in your blood pressure. Avoid taking Azilsartan Medoxomil+cilnidipine if you are pregnant. Azilsartan Medoxomil+cilnidipine should not be used in nursing mothers unless clearly necessary. So, inform your doctor if you are a nursing mother. Drive or operate machinery only if alert, as Azilsartan Medoxomil+cilnidipine may cause dizziness. Avoid alcohol consumption as it may cause unpleasant side effects. Keep your doctor informed about your health condition and medications to avoid side effects.
Drug Interactions
Drug-Drug Interactions: Azilsartan Medoxomil+cilnidipine may interact with other blood pressure treating medicines (e.g. aliskiren, enalapril, ramipril), diuretics medications (e.g. amiloride), anti-seizure medication (e.g. phenytoin), antibiotic (e.g. rifampicin, erythromycin)
Drug-Food Interactions: Alcohol consumption should be avoided while taking Azilsartan Medoxomil+cilnidipine.
Drug-Disease Interactions: People with diabetes, angioedema, hypotension, CHF, hyperkalemia, renal artery stenosis, renal impairment, liver disease, and renal impairment should inform the doctor before taking Azilsartan Medoxomil+cilnidipine.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionAvoid alcohol consumption with Azilsartan Medoxomil+cilnidipine as it may cause increased dizziness.
Pregnancy
cautionAzilsartan Medoxomil+cilnidipine is not recommended during pregnancy since it may harm the baby. Consult your doctor before taking Azilsartan Medoxomil+cilnidipine if you plan to become pregnant or are already pregnant.
Breast Feeding
cautionPlease consult your doctor before taking Azilsartan Medoxomil+cilnidipine if you are breastfeeding. Your doctor will decide whether Azilsartan Medoxomil+cilnidipine can be taken during lactation.
Driving
cautionAzilsartan Medoxomil+cilnidipine may cause side effects like dizziness or tiredness. Hence, it is recommended not to drive or operate machinery until you are alert.
Liver
cautionLet your doctor know if you have/had the liver disease before taking Azilsartan Medoxomil+cilnidipine. Your doctor will prescribe only if the benefits outweigh the risks.
Kidney
cautionLet your doctor know if you have/had kidney disease before taking Azilsartan Medoxomil+cilnidipine. Your doctor will prescribe only if the benefits outweigh the risks.
Children
unsafeSafety and efficacy of Azilsartan Medoxomil+cilnidipine have not been established in children.
Habit Forming
Diet & Lifestyle Advise
- Keep your weight under control with a BMI of 19.5-24.9.
- Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help lower your blood pressure by about 5 mm of Hg.
- Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.
- Limit sodium chloride (table salt) intake in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.
- If you are taking alcohol, then only one serving for women and two serving for men is advisable.
- Quitting smoking is the best strategy to lower the risk of heart disease.
- Avoid chronic stress, as it can raise your blood pressure. Enjoy and spend time with your loved ones to cope with stress and practice mindfulness techniques.
- Monitor your blood pressure daily, and immediately contact your doctor if there is too much fluctuation.
- Try to include heart-healthy omega-3 fatty acid-containing food drinks in your daily diet. You can also use low-fat cooking oils like olive oil, soybean oil, canola oil, and coconut oil to help lower your elevated blood pressure.
Special Advise
- Check your daily blood pressure, and if you notice any fluctuations, please consult a doctor.
- Cilnidipine in Azilsartan Medoxomil+cilnidipine may interfere with specific lab tests like parathyroid and protein-bound iodide tests; hence, inform the person doing the tests that you are taking Azilsartan Medoxomil+cilnidipine.
- Regular monitoring of blood glucose levels is advised in diabetic patients while using Azilsartan Medoxomil+cilnidipine.
Patients Concern
Disease/Condition Glossary
Hypertension: Hypertension is a medical condition in which blood pressure is elevated persistently in the arteries. It is considered an essential risk factor for cardiovascular diseases and can be caused by obesity, diabetes, smoking, high salt intake, stress, lack of physical activity or ageing. Blood pressure is measured in the ratio of systolic pressure to diastolic pressure. Systolic pressure is the pressure when the heart pumps blood out. On the other hand, diastolic pressure is the pressure when your heart is at the resting stage between heartbeats. The ideal blood pressure ranges between 90/60 mmHg and 120/80 mmHg. It is considered high blood pressure if it is 140/90 mmHg or greater.
FAQs
Azilsartan Medoxomil+cilnidipine is used to treat Hypertension (High Blood Pressure).
Azilsartan Medoxomil+cilnidipine helps relax the blood vessels, allowing the blood to flow more smoothly. This helps the heart pump blood easily throughout the body, lowering blood pressure.
Cilnidipine in Azilsartan Medoxomil+cilnidipine may affect blood sugar levels in people with diabetes. Hence, monitoring your sugar levels while taking Azilsartan Medoxomil+cilnidipine regularly is advised. Your doctor may adjust the dose accordingly. Please seek medical advice for more information before starting Azilsartan Medoxomil+cilnidipine.
Even though your blood pressure becomes normal after using Azilsartan Medoxomil+cilnidipine, it may switch back to high ranges if you stop using it. Therefore, continue taking Azilsartan Medoxomil+cilnidipine for as long as your doctor has advised.
Consult your doctor before taking Azilsartan Medoxomil+cilnidipine with other medicines as Azilsartan Medoxomil+cilnidipine may increase the rate of gastrointestinal transit, simultaneously affecting the absorption of other orally administered medicines.
